Case Studies - - OPERATIONAL EXCELLENCE

KUDOS - Sharing collective process insight

Right across the process industries manufacturers use similar unit operations and face similar challenges as they strive to optimise their performance. At the same time, collaborative research projects often struggle to disseminate fresh insights about process technologies widely and in ways that endure. Britest Knowledge and Understanding Domains (KUDOS) collate process understanding, generated through projects, in a form that allows process sector companies to learn about different process operations and challenges.

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- EFFECTIVE COLLABORATION- KNOWLEDGE SHARING- OPERATIONAL EXCELLENCE- TECHNICAL FACILITATIONProcess DesignSkills DevelopmentTraining




Mapping the Manufacturing Value Stream to Spot Improvement Opportunities

When the technical team responsible for a market-leading medicine within a high-profile global, science-led biopharmaceutical company wanted to establish where process improvement opportunities existed for the product line, they turned to a Britest study to summarise process inputs, outputs and key information. The study allowed the manufacturing value stream to be seen end-to-end in great detail for the first time ever, highlighting value gaps and the scale and location of improvement opportunities, and catalysed both "quick-win" actions, and a plan to deliver the pipeline of improvement projects identified.

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- OPERATIONAL EXCELLENCE- WHOLE PROCESS UNDERSTANDINGPharmaProcess ImprovementTOOL - Process Information Summary Map




Improving Access to Organisational Knowledge: A Visual Understanding of a Key Unit Operation

A large company in the pharmaceuticals sector has been able to transform the availability and hence use of existing information and existing work on the commonly used isolation technique of pressure filtration. Britest Rich Pictures and Cartoons provided an elegant format to portray and summarise current information and understanding, and by digitising these into a dedicated internal site, AstraZeneca were able to produce an easy to use guide to pressure filtration development.

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- EFFECTIVE COLLABORATION- KNOWLEDGE SHARING- OPERATIONAL EXCELLENCESkills DevelopmentTOOL - Rich Pictures




Improving Food Operations Training

Stu Brew is Europe’s first student run microbrewery, helping students gain hands on experience at running a business, operating equipment and researching sustainability improvements for the brewing process. This case study describes how Britest tools have been used by Newcastle University to support operation of the microbrewery, and in particular to help train student operators to enhance process understanding.

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- KNOWLEDGE SHARING- OPERATIONAL EXCELLENCEBiotechnologyFoodTOOL - Process Definition DiagramTOOL - Rich PicturesTraining




Rapid optimisation of a new process in Pharmaceutical API manufacture

Read how Britest successfully provided the structured approach needed by a process development centre within a large multi-national pharmaceutical business to optimise a new process in a very short time period.

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- OPERATIONAL EXCELLENCE- WHOLE PROCESS UNDERSTANDINGPharmaProcess Design




Britest Improvement Study to Increase Throughput by 50%

This case study describes the elements of a Britest throughput improvement study carried out by a custom synthesis manufacturer to meet an identified customer need to increase process throughput by at least 50% within three years, which was successfully delivered by halving batch times.

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- OPERATIONAL EXCELLENCECustom ManufactureProcess DesignProcess ImprovementTOOL - Driving Force AnalysisTOOL - Initial Screening AnalysisTOOL - Process Definition DiagramTOOL - Process Information Summary MapTOOL - Rich PicturesTOOL - Transformation Map




Challenging ideas on an established manufacturing process

How do you reduce costs and drive value when you've been operating a process for 25 years? This Britest study with a fine chemical company did exactly that by challenging established idea of what was and wasn't optimal in the process chemistry to speed up and simplify the reaction route.

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- OPERATIONAL EXCELLENCE- WHOLE PROCESS UNDERSTANDINGCustom ManufactureProcess DesignSpeciality Chemicals