Protocols for Liquid Chromatography method validations under GMP often require complex dilution schemes with many opportunities for errors in execution. This necessitates inefficient extra checks, and duplication of work (further consuming valuable API). Presenting the dilution schemes visually using a Britest ‘Rich-PrISM’ has made the dilution schemes far easier for analysts to follow. The result is substantially reduced lead time and resource consumption, and all protocols executed 'right first time'.
Right across the process industries manufacturers use similar unit operations and face similar challenges as they strive to optimise their performance. At the same time, collaborative research projects often struggle to disseminate fresh insights about process technologies widely and in ways that endure. Britest Knowledge and Understanding Domains (KUDOS) collate process understanding, generated through projects, in a form that allows process sector companies to learn about different process operations and challenges.
A large company in the pharmaceuticals sector has been able to transform the availability and hence use of existing information and existing work on the commonly used isolation technique of pressure filtration. Britest Rich Pictures and Cartoons provided an elegant format to portray and summarise current information and understanding, and by digitising these into a dedicated internal site, AstraZeneca were able to produce an easy to use guide to pressure filtration development.
Stu Brew is Europe’s first student run microbrewery, helping students gain hands on experience at running a business, operating equipment and researching sustainability improvements for the brewing process. This case study describes how Britest tools have been used by Newcastle University to support operation of the microbrewery, and in particular to help train student operators to enhance process understanding.
This case study summarises how Infineum and Britest together developed an approach to effectively embed Britest in the organisation and the value gained.
Read how a Britest facilitator was able to help a contract manufacturing organisation who did not know the Britest tools identify a common language for effective technology transfer.